Kadcyla (trastuzumab emtansine)

Information on this site is not intended as medical advice and should not be used as a substitute for consulting with qualified doctor.

Kadcyla is an Antibody Drug Conjugate (ADC), which combines the HER2-targeting properties of Herceptin (trastuzumab) and the cytotoxic chemotherapy agent DM1. In Kadcyla, trastuzumab and DM1 are joined together using a ‘stable linker’ to deliver DM1 directly to HER2-positive cancer cells.1

Kadcyla is approved as a single agent in the US, EU and many other countries for the treatment of people with HER2-positive advanced breast cancer who previously received Herceptin and taxane chemotherapy, separately or in combination.1

 

In Bangladesh Kadcyla is approved for the following indications.2

Breast Cancer
Metastatic Breast Cancer (MBC)

Kadcyla, as a single agent, is indicated for the treatment of patients with HER2-positive, unresectable locally advanced or metastatic breast cancer who have received prior treatment with trastuzumab and a taxane. Early

Breast Cancer (EBC)

Kadcyla, as a single agent, is indicated for the adjuvant treatment of patients with HER2- positive early breast cancer who have residual disease after pre-operative systemic treatment.

 

For more disease and medicine related queries you may discuss with your physician.

 

In Bangladesh Kadcyla is available as

Vials 100 mg

Vials 160 mg

 

Winning the battle against breast cancer

Breast cancer is the leading cancer among all cancer types in women worldwide including Bangladesh. About 1 out of every 4 cancer patients in the world suffers from this cancer. However, the good news is, if the disease can be diagnosed at an early stage and proper treatment can be given it can be cured in 99% cases, which comes down to 27% for Advance Stage. Although most of the cancers are difficult to diagnose at an early stage, breast cancer is often more likely to be diagnosed early. All you need is the right information and awareness. You can diagnose the disease at an early stage through regular breast examinations (BSE).

References

1. Global Website: Products – Kadcyla. [Internet; cited 2018, November 08]. Retrieved from https://www.roche.com/products/product-details.htm?productId=64b71dad-d4bc-470a-8307-e56de10428ed

2. Kadcyla Product Information _ FE-English Ro – 053040 _ January 2019